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Pretransplant Assessment of Mortality Score

This calculator is designed to calculate a “PAM score” (Pretransplant Assessment of Mortality Score) that estimates the probability of survival at 2 years after allogeneic hematopoietic stem cell transplantation with myeloablative conditioning for treatment of a hematologic malignancy. The original scoring algorithm was developed and validated using a large cohort (1990 to 2002) at the Seattle Cancer Care Alliance/Fred Hutchinson Cancer Research Center (Annals of Internal Medicine, 2006 Mar 21;144(6):407-14). We recently published a study re-evaluating and revising the PAM model using a contemporary cohort (2003-2009) to update and recalibrate its predictive capability (Au et al., Biology of Blood and Marrow Transplantation. 2015; in press). The results below reflect the updated PAM model.

To use this calculator, enter data for the nine clinical and laboratory variables below using the drop down menus.

PAM Calculator


Donor Relationship

Disease Risk

Percent of predicted forced expiratory volume in one-second (FEV1)

Cytomegalovirus (CMV) serology

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