This calculator is designed to calculate a “PAM score” (Pretransplant Assessment of Mortality Score) that estimates the probability of survival at 2 years after allogeneic hematopoietic stem cell transplantation with myeloablative conditioning for treatment of a hematologic malignancy. The original scoring algorithm was developed and validated using a large cohort (1990 to 2002) at the Seattle Cancer Care Alliance/Fred Hutchinson Cancer Research Center (Annals of Internal Medicine, 2006 Mar 21;144(6):407-14). We recently published a study re-evaluating and revising the PAM model using a contemporary cohort (2003-2009) to update and recalibrate its predictive capability (Au et al., Biology of Blood and Marrow Transplantation. 2015; in press). The results below reflect the updated PAM model.
To use this calculator, enter data for the nine clinical and laboratory variables below using the drop down menus.